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HYPERHIDROSIS TREATMENT USING THE Nd: YAG 1440nm WAVELENGTH LASER WITH TARGETED ENERGY DELIVERY
Bruce Katz, M.D.1, David Cangello, M.D., MSc.2.
1Mount Sinai School of Medicine, New York, NY, USA, 2Manhattan Eye Ear Throat Hospital, New York, NY, USA.

HYPERHIDROSIS TREATMENT USING THE Nd: YAG 1440nm WAVELENGTH LASER WITH TARGETED ENERGY DELIVERY
Background: Primary Focal Axillary Hyperhidrosis is a chronic disorder of sweating within the axilla that creates significant impairment of an individual’s daily activities and psychological well-being.
Severe hyperhidrosis affects 2.8% of the overall population (7.8 million individuals) and it is estimated that axillary hyperhidrosis effects over 1.4% of the U.S. population representing over 4 million individuals, a prevalence comparable to that of psoriasis.
Objective: The purpose of this study is to determine the efficacy of a single treatment utilizing a new fiber to disrupt the sweat glands located in the axilla.
Methods: A total of 15 patients with moderate to severe hyperhidrosis of the axilla (HDSS scores of 3 and 4) were enrolled in this prospective IRB controlled study.
Subjects were treated in a single session with a 1440nm pulsed Nd:YAG laser with a new fiber design designed to deliver targeted energy.
Efficacy was measured at three and six months through both subjective and objective quantitative means including patient and physician questionnaires, HDSS score, and quantitative improvements utilizing digital software analysis (Image J software by N.I.H.) and histology results.
Results: A total of 15 patients were treated. Minimal adverse effects were reported from patient diaries and physician assessment. High improvement by subject evaluation and subjective physician evaluation was reported. The average HDSS score improved by 2 points. Image J software analysis reported an average of 84% reduction in sweat area volume at three months and 99% at six months. Histologic reports demonstrated a reduction in both eccrine and apocrine glands.
Conclusion: The 1440 wavelength combined with the Sidelight 3D™ fiber delivery system is an effective tool in the treatment of severe hyperhidrosis.


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